Dr. Evans was a keynote speaker at IMFAR 2012. His talk centered around the work that is being done based on the data collected from the longitudinal study of normal brain development at NIH. He spoke extensively about correlates that can be read from the data, for example, the relationship between cortical structure and things like IQ and testosterone levels. It would be impossible to capture the incredible amount of information in 140 character bites, but as an outline, we hope it can give you a starting point for further research. Errors, omissions and misspellings are mine.-JBM
[<a href="http://storify.com/jennyalice/alan-evan-phd-structural-connectivity-in-neurodeve" target="_blank">View the story "Alan Evans, PhD: Structural Connectivity in Neurodevelopment IMFAR 2012 " on Storify</a>]<h1>Alan Evans, PhD: Structural Connectivity in Neurodevelopment IMFAR 2012 </h1><h2>from the meeting materials: A. C. Evans: The NIH MRI Study of Normal Brain Development is a multi-centre, mixed cross-sectional and longitudinal study of anatomical and behavioural maturation in 500 typically-developing children ages 0-18 years.</h2><p>Storified by · Thu, May 24 2012 01:35:37</p><div>I tweeted this entire thread using Evan instead of Evans. Apologies to Dr. Evans.-JBM<br></div><div>Alan Evan, PhD Structural Connectivity in Neurodevelopment #IMFAR2012Jennifer Byde Myers</div><div>Dr. Evans is from Montreal Neurological Institute, Montreal, QC, Canada http://www.mni.mcgill.ca/<br></div><div>From the conference materials: <br>This sessions aimed to cover:<br><p>(i) age-appropriate structural atlasing.</p><p>(ii) Cortical correlates of behavioral metrics, e.g. IQ, testosterone level, aggressivity/anxiety.</p><p>(iii) age-related changes in structural network topology derived from cortical thickness analysis. </p></div><div>Evan Info on NIH MRI study of Normal Brain Development (NIHPD) & MRI-derived neuroanatomical maturation #IMFAR2012Jennifer Byde Myers</div><div>Information on Dr. Evans' additional research http://www.researchgate.net/researcher/39829705_Alan_C_Evans<br></div><div>Evan NIH MRI study NIHPD : Collection o fbrain and behavior children 4.5-18.3 & a younger cohort, 10days-4.5 #IMFAR2012Jennifer Byde Myers</div><div>Evan Age-appropriate templates of brain, mapped white matter. Difference b/t adult & child brain showing overlap & differences #IMFAR2012Jennifer Byde Myers</div><div>Evan Data is downloadable from McGill website (will try to get link later) #IMFAR2012Jennifer Byde Myers</div><div>Evan Slides howing maturation of mylenation process #IMFAR2012Jennifer Byde Myers</div><div>Watching Dr. Evan & am a little moved b/c info just wasn't available when myBoy was little & we talked re: grey v white matter. #IMFAR2012Jennifer Byde Myers</div><div>Animated slideshow birth --> 4.5 unbelievably cool. RT @jennyalice: Evan Slides howing maturation of mylenation process #IMFAR2012Shannon Rosa</div><div>Evan Growth rate videos Absolute growth..happens so quickly in 1st year of life #IMFAR2012Jennifer Byde Myers</div><div>Evan in brain growth left hemisphere develops 1st, right catches up very quickly (all this is happening before age 3) #IMFAR2012Jennifer Byde Myers</div><div>Evan Rapid expansion up until age 3 then slower development over time (study looke dat up to 20) #IMFAR2012Jennifer Byde Myers</div><div>Evan Brain/behavior correlations that arise from this database many diff trials/research 40 instruments to look at vs MRI images :#IMFAR2012Jennifer Byde Myers</div><div>Evan Data is there, just create a hypothesis & analize the database. one example: cortical thickness vs IQ study #IMFAR2012Jennifer Byde Myers</div><div>Evan More examples: Cortical thickness vs testerone in both males and females. Child behavior checklist v cortical thickness #IMFAR2012Jennifer Byde Myers</div><div>Evan Cortical Thickness. Types of connectivity: white matter, functional and gre matter#IMFAR2012Jennifer Byde Myers</div><div>Evan: cortical thicknesss (CT) may indicate chronic functional connectivity #IMFAR2012Jennifer Byde Myers</div><div>Evan Cortical Thickness. Types of connectivity: white matter, functional and grey matter #IMFAR2012Jennifer Byde Myers</div><div>The database has been made publicly available since 2007 and has gone through 5 releases since 2011.</div><div>Evan Anatomical thickness : regional correlation in CT across subjects, after removing gender-age interactions & mean thickness #IMFAR2012Jennifer Byde Myers</div><div>Evan: Slides which show brain networks as graphs: small world: which show few long path lengths more short path lengths #IMFAR2012Jennifer Byde Myers</div><div>Evan: Cortical thickness in ASD: AD-r social scores, differences in frontal gyrus. #IMFAR2012Jennifer Byde Myers</div><div>Evans: cortical thickness related to enhanced pitch perception in pts with #autism .explanation for sensitivity to sound?? #IMFAR2012Dr. Raphael Sharon</div><div>RT @Peter_Autisme: Evans confirms local hyperconnectivity and long range underconnectivity hypothesis in autism at #IMFAR2012Loek Mak-Peters</div><div>Evan: IBIS (infant Brain Imaging Stiudy) http://www.ibis-network.org more data #IMFAR2012Jennifer Byde Myers</div>
